Consider The Evidence: Med/Peds Journal Roundup

March 7, 2006

Attack of the clones: Community Aquired MRSA

Filed under: annals of internal medicine, infectious disease, lancet, MRSA — medblog @ 10:00 pm

Community Aquired MRSA and the USA 300 clone are making news in two journals this week… Get used to those stupid yellow gowns 😦
AnnalsIM 3/7 – A study by King et al. in The Annals of Internal Medicine documents the epidemiology of community aquired MRSA in a major hospital system in Atlanta, GA. The study included patients with community aquired skin and soft tissue infections due to Staph aureus. The results show that a majority (63%) of S. aureus isolates were methicillin resistant. 99% of the CA-MRSA samples that were further analyzed were the USA 300 clone.

A second paper, by Graham et al., analyzed the NHANES data on nasal swabs taken in a population sample. They found that, “The prevalence of colonization with S. aureus and with MRSA was 31.6% and 0.84%, respectively, in the noninstitutionalized U.S. population.”

Lancet 3/4 – An article in the Lancet by Diep et al. details the genome of the USA300 clone and the particular elements that lead to its epidemiology and virology. Frankly, much too dense for me to read more than the abstract – but I’m glad somebody else cares…

P. L. Graham, III, S. X. Lin and E. L. Larson. “A U.S. Population-Based Survey of Staphylococcus aureus Colonization.” Ann Intern Med 2006; 318-325.
M. D. King, B. J. Humphrey, Y. F. Wang, E. V. Kourbatova, S. M. Ray and H. M. Blumberg
“Emergence of Community-Acquired Methicillin-Resistant Staphylococcus aureus USA 300 Clone as the Predominant Cause of Skin and Soft-Tissue Infections. ” Ann Intern Med 2006; 309-317.

Diep BA, Gill SR, Chang RF, Phan TH, Chen JH, Davidson MG, Lin F, Lin J, Carleton HA, Mongodin EF, Sensabaugh GF, Perdreau-Remington F. ” Complete genome sequence of USA300, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureus.” Lancet. 2006 Mar 4;367(9512):731-9.

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3 Comments »

  1. *HOW I KICKED MRSA*

    NOTE: EVERYTHING THAT I AM STATING IN THESE PARAGRAPHS IS ONLY MY OWN ADVICE. I AM NOT A DOCTOR, THIS IS JUST WHAT WORKED FOR ME. I TOOK THE ADVICE OF DOCTORS, WHAT I SEARCHED ONLINE AND RANDOM THOUGHTS AND PUT THEM TO THE TEST. LUCKILY, ALL OF THIS WORKED FOR ME AND I WISH I WOULD HAVE HAD SOMETHING LIKE THIS TO READ IN THE BEGINNING. THESE ARE ONLY MY OWN SUGGESTIONS. I STRONGLY SUGGEST YOU TRYING THEM, YOU HAVE NOTHING TO LOSE.

    *Antibiotics. I have been prescribed BACTRIM and also CLINDAMYCIN at different times.

    *HIBICLENS cleanser. This is an antiseptic/antimicrobial skin cleanser. It is a bright red liquid that comes in an 8 oz. teal colored plastic bottle. It should be found over the counter at your pharmacy. Use as a body scrub (best to avoid face & genitalia) daily for 2 weeks straight.

    *MUPIROCIN ointment. This is a prescription antibiotic ointment (comes in a small tube) to put on the skin. Put it on your MRSA breakouts as soon as you notice them coming and it should shrink them so that you don’t have to open them up and drain them. This will save you a lot of pain. Also, use a q-tip to apply a thin layer under your nose. Morning and night unless you shower or wash your face throughout the day, reapply. This will make an invisible barrier to help reduce the chance of staph entering your nose. Try your hardest to keep your fingers away from your nose at all times. Also, at night I used a nail brush and scrubbed under my finger nails with HIBICLENS then used a q-tip to apply a thin layer of MUPIROCIN under my finger nails since staph lives under your nails.

    *Wash your hands like crazy and keep a bottle of hand sanitizer in your purse/pocket.

    *One ER doctor told me never to cover a breakout because it needs to breathe. That’s crazy; you do not want anyone else to come into contact with an active breakout. Use a band-aid/bandage. You will find that you may hear many different things from many different doctors. There are so many different strains and they are rapidly growing so not everyone is up to speed on what works and what should be done.

    *I cannot stress this enough… DO NOT SHARE RAZORS!!! I believe this is how I got MRSA, by sharing my boyfriend’s razor. If you are close to someone else that has MRSA, the two of you can keep giving it back and forth to each other. Also, you keep giving it back to yourself. I am no longer surrounded by any one else that has it, which is great, but to avoid giving it back to myself I keep a cup filled with rubbing alcohol in my bathroom and after every single use of my razor I soak it in the cup. I really feel that this is important.

    *As you are battling this, you must keep your house as sterile as possible. I like to use natural cleaners in my house but while I was dealing with this I didn’t want to mess around. I bought very strong bathroom spray with bleach in it and kept Clorox wipes in my house. Keep your bathroom clean. Also, change your sheets and towels more often than you normally would. Remember, if you are in the bathroom extracting a MRSA breakout, you pretty much have to tell yourself that it’s a bio-hazard area. No one else should be there unless you really need help. EVERYTHING needs to be cleaned once you are done. Any towels used must be kept separately and washed in very hot water and possibly bleach. Wipe down every area you (and what has come out of you) have touched. Remember that what comes out of you is toxic.

    GOOD LUCK!!!

    Comment by tambutt — October 18, 2007 @ 4:13 pm

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