Consider The Evidence: Med/Peds Journal Roundup

June 30, 2006

statins sort of might possibly be antioxidants

Filed under: Uncategorized — medblog @ 6:34 am

JAMA – According to an article by Klein et al., age-related cataract formation has been thought to be associated with oxidative stress. In addition, statins have been shown to have antioxidant properties.

So, in the age-old tradition of testing two unproven hypotheses against each other, the researchers looked at data from the observational Beaver Dam Eye study. The data showed that use of statins was associated with a significant reduction in risk of nuclear cataract – the most common type of age-related cataract.

Possibly the reason behind the possible anti-cancer effects of statins (if such an effect actually exsists)? Interesting idea, especially since most anti-oxidant trials have failed to show any clinical effect in RCTs.


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