Consider The Evidence: Med/Peds Journal Roundup

April 17, 2008

Yes, Statins do everything – even lower BP

Filed under: archives of internal medicine, hypertension — medblog @ 5:02 pm

What could be crazy enough to end a 4 month hibernation of CTE?

Archives Int Med 4/08 – The UCSD Statin study yielded further evidence that statin treatment reduces blood pressure (although not by much) The RCT enrolled over 900 subjects without known CVD or diabetes. The idea was to independently assess the effect on BP. There was no inclusion / exclusion criteria regarding baseline BP. Subjects were randomized to pravastatin, simvastatin, or placebo.

Treatment with a statin resulted in about a 2-2.5 point drop in SBP and DBP. The treatment was stopped at 6 months, and the blood pressures returned to baseline by month 8 – further suggesting that this was a true effect.

Beatrice A. Golomb; Joel E. Dimsdale; Halbert L. White; Janis B. Ritchie; Michael H. Criqui
Reduction in Blood Pressure With Statins: Results From the UCSD Statin Study, a Randomized Trial
Arch Intern Med. 2008;168(7):721-727.

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